Research Articles
Decoding Functional Insights: A Practical Guide to GO Term Analysis of Epigenomic Datasets for Biomedical Research
This article provides a comprehensive guide to the functional analysis of epigenomic datasets using Gene Ontology (GO) terms, tailored for researchers and drug development professionals.
From Raw Reads to Biological Insight: A Complete Protocol for ATAC-seq Data Processing and Analysis
This article provides a comprehensive, step-by-step protocol for the processing and analysis of Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) data, tailored for researchers and bioinformaticians.
From Raw Reads to Biomarkers: A Practical Guide to WGBS and RRBS Methylation Data Analysis for Clinical and Research Applications
This article provides a comprehensive, step-by-step guide to analyzing DNA methylation data from Whole-Genome Bisulfite Sequencing (WGBS) and Reduced Representation Bisulfite Sequencing (RRBS).
MOFA+ for Multi-Omics Integration in Cancer Research: A Statistical Framework for Unifying Biological Complexity
This article provides a comprehensive guide to Multi-Omics Factor Analysis v2 (MOFA+), a powerful statistical framework for integrating diverse molecular data in cancer research.
Integrating Multi-Omics with AI: Unlocking Precision Subtypes for Breast Cancer Prognosis and Therapy
This article provides a comprehensive guide for researchers and drug development professionals on multi-omics integration for breast cancer subtyping.
ChIP-Seq for Transcription Factor Binding Sites: From Foundational Analysis to Advanced Applications in Biomedical Research
This article provides a comprehensive guide to transcription factor binding site analysis using ChIP-seq, tailored for researchers and drug development professionals.
From Data to Discovery: A Practical Guide to Integrating RNA-seq and Epigenomic Data for Precision Medicine
This article provides a comprehensive guide for researchers and drug development professionals on integrating RNA-seq and epigenomic data.
Mastering ChIP-seq Analysis: A Comprehensive Guide to Peak Calling, Annotation, and Best Practices
This article provides a complete practical guide for researchers and drug development professionals on analyzing ChIP-seq data, from foundational concepts to advanced applications.
Decoding Epigenetic Changes: A Comprehensive Guide to Differential Peak Analysis in Biomedicine
This article provides a comprehensive guide to differential peak analysis, a cornerstone of modern epigenomics for discovering regulatory elements driving cellular identity and disease.
ChIPseeker: A Comprehensive Guide to Epigenomic Data Preparation, Annotation, and Analysis for Biomedical Research
This article provides a complete guide for researchers, scientists, and drug development professionals on utilizing ChIPseeker, a powerful Bioconductor R package, for epigenomic dataset analysis.