Discover how Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation, potentially repurposing cancer drugs for inflammatory conditions.
Discover how epigenetic mechanisms regulate inflammation and organ dysfunction after surgery, and the potential for personalized epigenetic therapies.
Explore the cellular mechanisms behind COPD including cellular senescence, inflammation, EMT, and groundbreaking research on potential treatments.
Discover how epigenetic memory in intestinal cells explains IBD inflammation recurrence and new treatment possibilities.
Explore the cellular mechanisms and pathogenesis of COPD, from inflammatory cascades to genetic factors and emerging treatments.
Discover how epigenetic memory in pancreatic cells creates a lasting record of inflammation that can lead to cancer development, and what this means for future treatments.
Comprehensive review of 2025 advances in gout research, including novel pathophysiology mechanisms, therapeutic innovations, and clinical implications.
Discover how LKB1 protein acts as a master regulator of inflammation through CRTC2-dependent epigenetic remodeling and its implications for disease therapy.
Discover how palmitic acid reprograms immune cells through trained immunity, enhancing pathogen defense but risking hyperinflammation in metabolic diseases.