Research Articles
The Epigenetic Triad: Decoding the Interplay of Non-Coding RNAs, DNA Methylation, and Histone Modifications
This article provides a comprehensive analysis of the sophisticated crosstalk between non-coding RNAs (ncRNAs), DNA methylation, and histone modifications—the core pillars of epigenetic regulation.
Epigenetic Regulation of Pluripotency and Differentiation: Mechanisms, Applications, and Therapeutic Frontiers
This article provides a comprehensive analysis of the epigenetic mechanisms governing stem cell pluripotency and cellular differentiation, tailored for researchers and drug development professionals.
Epigenetic Mechanisms in Neurodevelopmental Disorders: From Molecular Pathways to Clinical Translation
This review synthesizes current research on the critical role of epigenetic mechanisms—including DNA methylation, histone modifications, and non-coding RNAs—in the pathogenesis of neurodevelopmental disorders (NDDs).
Histone Variants and Chromatin Dynamics: Master Regulators of Cell Fate in Development and Disease
This article synthesizes current knowledge on how histone variants, the non-allelic isoforms of canonical histones, act as pivotal regulators of chromatin dynamics to control cell fate decisions.
The Gut Microbiome as an Epigenetic Regulator: Molecular Mechanisms, Research Methodologies, and Therapeutic Applications
This article synthesizes current research on the dynamic interplay between the gut microbiome and the host epigenome, a field with profound implications for precision medicine.
Transgenerational Epigenetic Inheritance in Mammals: Evidence, Mechanisms, and Clinical Implications
This article provides a comprehensive analysis of transgenerational epigenetic inheritance (TEI) in mammals for a scientific audience of researchers and drug development professionals.
Epigenetic Regulatory Networks: Master Controllers of Cellular State in Health and Disease
This article provides a comprehensive exploration of the Epigenetic Regulatory Network (ERN), a complex system of interdependent modifications that dictates cellular identity and function.
The Silent Passenger: How Epstein-Barr Virus Hijacks Our Cells to Cause Cancer
Discover how Epstein-Barr virus (EBV), present in 95% of adults, manipulates cellular machinery to cause cancer through molecular hijacking.
CRISPR-Cas9: Revolutionizing Our Fight Against Cancer
Explore how CRISPR-Cas9 gene editing technology is transforming cancer research and treatment through precision genetic engineering.
Unlocking Genetic Diversity: How African Pangenomes Are Revolutionizing Precision Medicine
Discover how African pangenome research is addressing genomic reference bias and advancing equitable precision medicine through groundbreaking research.